Integrum DuoGen®: Two-Phase Wound Care for Livestock
Wounds and damaged mucosa are more than a welfare issue for livestock. They cause pain, reduce appetite and open the door to infection. Integrum DuoGen® was developed to address both sides of the problem: first it controls pathogens on the wound, then it supports the tissue in repairing itself.
One system, two phases
Integrum DuoGen® is a two-phase system for managing skin and tissue lesions in livestock. It is based on the principles of wound biology, tissue repair dynamics and advanced antimicrobial science, and works in a staged, targeted way.
Phase one: microbial and viral control. The first phase inactivates a broad range of pathogens within a short contact time. It disrupts the structures pathogens need to survive, such as their protein surfaces, cell membranes and genetic material. It is especially effective against non-enveloped viruses, which are usually highly resistant to chemical agents. Thanks to its low cytotoxicity and good tissue compatibility, it can be used on open wounds without burning or irritation.
Phase two: activating tissue repair. The second phase supports the body’s own healing process. It creates a moist healing microenvironment, stimulates fibroblast activity and collagen formation, and speeds up the regrowth of skin over the wound. By calming inflammation and preventing it from becoming chronic, it helps the lesion move into the healing phase sooner. It also reduces the formation of fibrotic scar tissue, for better-quality healing and stronger tissue.
The advantages at a glance
- Reduces the microbial load without damaging tissue
- Creates good conditions for repairing cells
- Effective against resistant pathogens, especially non-enveloped viruses
- Better healing outcomes by keeping the wound moist and reducing chronic inflammation
- Stronger tissue and a lower risk of secondary infection
- Calms inflammation and speeds up tissue repair
- Soothes wounds and damaged mucosa
How it is applied
Both phases are sprayed onto the cleaned lesion. Phase one is applied first and left to act for one to two minutes. Phase two follows once the surface is moist but no longer wet. The treatment is typically repeated two to three times a day, as directed by a veterinarian. Animals usually show better appetite and less pain within about two days.
Where we stand, and what comes next
Integrum DuoGen® has successfully passed all required laboratory and dermatological tests. The next step is clinical trials with veterinarians in real-world conditions, with a focus on animals affected by foot-and-mouth disease (FMD). These trials will prepare the product for market registration.
To get there faster, we are looking for strategic partners in veterinary medicine, animal health and distribution.
Interested in Integrum DuoGen® or a partnership? Contact us to learn more.